Details for gene set NCI_GLYPICAN 1 NETWORK[GSEA]

Table: GSEA Results Summary

Dataset	set01_ATM_minus_versus_ATM_plus
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_GLYPICAN 1 NETWORK
Enrichment Score (ES)	-0.4862929
Normalized Enrichment Score (NES)	-2.221793
Nominal p-value	0.0
FDR q-value	6.957728E-5
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	IL5	11	22.605	0.0113	No
2	RBBP7	70	15.794	0.0169	No
3	CEBPB	74	15.638	0.0249	No
4	RAN	122	13.946	0.0300	No
5	YWHAQ	140	13.364	0.0362	No
6	SAP18	246	11.322	0.0373	No
7	RBL1	284	10.907	0.0412	No
8	CDK4	343	10.371	0.0440	No
9	HRAS	510	8.966	0.0410	No
10	DACT2	527	8.841	0.0448	No
11	STRAP	675	8.095	0.0423	No
12	GPC1	706	7.951	0.0450	No
13	MYC	869	7.330	0.0413	No
14	FCGR2B	927	7.120	0.0424	No
15	PLCG2	1020	6.821	0.0417	No
16	ARFIP2	1070	6.660	0.0429	No
17	EIF2A	1097	6.555	0.0451	No
18	FGR	1144	6.449	0.0464	No
19	XPO1	1342	5.926	0.0403	No
20	INPPL1	1375	5.849	0.0419	No
21	E2F1	1414	5.788	0.0432	No
22	MAPK1	1423	5.768	0.0458	No
23	BLK	1450	5.692	0.0476	No
24	KPNB1	1789	5.095	0.0346	No
25	ATF1	1894	4.952	0.0323	No
26	EEF2K	1953	4.869	0.0322	No
27	PPARG	1999	4.807	0.0326	No
28	BAD	2011	4.790	0.0346	No
29	UBE2D3	2039	4.762	0.0358	No
30	CDKN2A	2159	4.589	0.0327	No
31	CAMK2G	2267	4.454	0.0301	No
32	MAX	2271	4.449	0.0323	No
33	PTPRK	2304	4.414	0.0331	No
34	NFATC2	2387	4.322	0.0316	No
35	WWP1	2601	4.108	0.0238	No
36	COL1A2	2620	4.091	0.0251	No
37	MAPKAPK2	2720	3.998	0.0226	No
38	APP	2740	3.986	0.0238	No
39	SH3BP5	2857	3.902	0.0205	No
40	MAPK12	2869	3.894	0.0220	No
41	TP53	2880	3.885	0.0236	No
42	CDKN1A	2944	3.835	0.0227	No
43	IL3	3065	3.756	0.0191	No
44	AKT1S1	3163	3.688	0.0165	No
45	EIF4A1	3164	3.687	0.0184	No
46	PPARGC1A	3371	3.518	0.0107	No
47	CASP3	3387	3.501	0.0118	No
48	MAP3K6	3427	3.476	0.0118	No
49	CASP9	3432	3.473	0.0135	No
50	FOSL1	3479	3.447	0.0131	No
51	KRAS	3504	3.433	0.0138	No
52	ATF3	3548	3.407	0.0136	No
53	IL2RA	3564	3.387	0.0147	No
54	EIF4EBP1	3974	3.161	-0.0026	No
55	BTK	3984	3.157	-0.0014	No
56	PPP5C	4007	3.142	-0.0008	No
57	PPP2R5D	4047	3.115	-0.0010	No
58	FLT1	4151	3.068	-0.0041	No
59	SLC3A2	4297	2.996	-0.0093	No
60	IBTK	4328	2.985	-0.0091	No
61	MAP2K3	4337	2.980	-0.0079	No
62	CTGF	4384	2.960	-0.0085	No
63	EIF4G1	4441	2.936	-0.0096	No
64	TCF3	4510	2.909	-0.0112	No
65	USF1	4723	2.825	-0.0196	No
66	HSPB1	4823	2.785	-0.0227	No
67	POU2F2	5005	2.719	-0.0297	No
68	CITED1	5063	2.698	-0.0309	No
69	POU2F1	5182	2.660	-0.0350	No
70	MAF	5280	2.628	-0.0381	No
71	RIPK1	5284	2.628	-0.0369	No
72	MEF2C	5401	2.593	-0.0409	No
73	DLX1	5416	2.586	-0.0402	No
74	CAMK2B	5454	2.573	-0.0406	No
75	YWHAG	5501	2.556	-0.0414	No
76	INSR	5561	2.539	-0.0428	No
77	AR	5621	2.521	-0.0442	No
78	ITGB5	5632	2.516	-0.0433	No
79	STMN1	5657	2.509	-0.0431	No
80	SOS1	5789	2.466	-0.0479	No
81	RHEB	5913	2.426	-0.0524	No
82	RUNX3	6067	2.376	-0.0582	No
83	MYOD1	6186	2.340	-0.0625	No
84	PIK3R1	6230	2.327	-0.0632	No
85	IFNG	6243	2.320	-0.0626	No
86	EGR4	6366	2.287	-0.0671	No
87	HCK	6566	2.233	-0.0751	No
88	PAK3	6721	2.192	-0.0811	No
89	FGF2	6738	2.186	-0.0807	No
90	NKX2-5	6765	2.181	-0.0808	No
91	SERPINE1	6848	2.155	-0.0835	No
92	FGFR1	6855	2.152	-0.0826	No
93	KPNA1	6863	2.150	-0.0818	No
94	MAP3K7	6975	2.124	-0.0858	No
95	SMAD3	6988	2.122	-0.0853	No
96	RAC1	7002	2.119	-0.0848	No
97	CD72	7056	2.104	-0.0861	No
98	IL10	7078	2.096	-0.0860	No
99	NFKB1	7091	2.093	-0.0855	No
100	FASLG	7259	2.047	-0.0922	No
101	CLTB	7302	2.037	-0.0930	No
102	CCND1	7333	2.028	-0.0934	No
103	RPS6KA5	7337	2.027	-0.0925	No
104	SERPINC1	7489	1.990	-0.0984	No
105	YAP1	7517	1.983	-0.0986	No
106	CAV1	7552	1.974	-0.0992	No
107	TH	7580	1.968	-0.0994	No
108	DAB2	7717	1.926	-0.1047	No
109	SLIT2	7873	1.889	-0.1109	No
110	PARD6A	7943	1.873	-0.1131	No
111	ESR1	7998	1.858	-0.1147	No
112	CD19	8029	1.852	-0.1151	No
113	IRF4	8141	1.829	-0.1193	No
114	FOXH1	8337	1.781	-0.1274	No
115	CD22	8363	1.778	-0.1276	No
116	RNF128	8389	1.773	-0.1278	No
117	SNTA1	8648	1.705	-0.1389	No
118	DUSP8	8849	1.661	-0.1473	No
119	CD79A	8876	1.654	-0.1477	No
120	PPP3CA	9099	1.601	-0.1571	No
121	SLC2A4	9107	1.600	-0.1566	No
122	YES1	9129	1.594	-0.1568	No
123	ETV1	9162	1.584	-0.1574	No
124	PPP3CC	9402	1.530	-0.1677	No
125	NFKBIB	9422	1.525	-0.1678	No
126	MAP3K4	9437	1.520	-0.1676	No
127	LAMA1	9608	1.483	-0.1747	No
128	PIAS3	9796	1.434	-0.1827	No
129	AKAP5	9904	1.409	-0.1869	No
130	PLA2G2A	10382	1.291	-0.2083	No
131	CALM1	10454	1.273	-0.2110	No
132	PRKCZ	10572	1.242	-0.2157	No
133	PPP2CB	10613	1.234	-0.2170	No
134	PLD2	10726	1.208	-0.2215	No
135	MAPK13	10765	1.197	-0.2227	No
136	CDK2	10991	1.139	-0.2325	No
137	PDE3B	11073	1.116	-0.2357	No
138	RPS6	11187	1.089	-0.2403	No
139	NRG1	11286	1.059	-0.2443	No
140	ZFYVE9	11608	0.964	-0.2587	No
141	BLNK	11697	0.938	-0.2623	No
142	DOK1	11766	0.915	-0.2650	No
143	CALM2	11871	0.882	-0.2693	No
144	DUSP10	11980	0.847	-0.2739	No
145	HNF4A	12271	0.762	-0.2870	No
146	AP2A1	12394	0.726	-0.2922	No
147	IL4	12402	0.724	-0.2922	No
148	TDGF1	12467	0.703	-0.2948	No
149	GSC	12535	0.679	-0.2975	No
150	JUN	12565	0.666	-0.2985	No
151	PPP1CA	12734	0.618	-0.3060	No
152	TBX21	13363	0.371	-0.3349	No
153	VDR	13391	0.360	-0.3360	No
154	PIM1	13451	0.338	-0.3385	No
155	CSF2	13564	0.288	-0.3436	No
156	RAP1A	13631	0.258	-0.3465	No
157	GADD45G	13718	0.218	-0.3504	No
158	FOXG1	13769	0.185	-0.3526	No
159	OCLN	13782	0.177	-0.3531	No
160	SFN	14174	-0.015	-0.3712	No
161	PLA2G4A	14318	-0.105	-0.3778	No
162	CDC25B	14334	-0.116	-0.3784	No
163	CDKN2B	14499	-0.220	-0.3859	No
164	REL	14913	-0.486	-0.4048	No
165	IFNB1	14917	-0.487	-0.4047	No
166	GSK3A	14949	-0.501	-0.4059	No
167	PTGS2	14970	-0.509	-0.4065	No
168	ZFYVE16	15026	-0.559	-0.4088	No
169	SAP30	15175	-0.663	-0.4153	No
170	TGIF2	15194	-0.674	-0.4158	No
171	SRC	15241	-0.705	-0.4175	No
172	CD40LG	15266	-0.717	-0.4183	No
173	DYNLRB1	15483	-0.867	-0.4278	No
174	SMAD2	15494	-0.876	-0.4279	No
175	BAMBI	15593	-0.940	-0.4319	No
176	GRB2	15610	-0.952	-0.4321	No
177	IRS1	15669	-0.991	-0.4343	No
178	MAP2K1	15741	-1.040	-0.4371	No
179	TNF	16079	-1.307	-0.4520	No
180	RIPK2	16143	-1.360	-0.4542	No
181	CTDSPL	16165	-1.381	-0.4545	No
182	TSC2	16253	-1.451	-0.4578	No
183	DAXX	16329	-1.510	-0.4604	No
184	PRKDC	16339	-1.517	-0.4601	No
185	ZAP70	16444	-1.608	-0.4640	No
186	E2F5	16561	-1.721	-0.4685	No
187	PRKACA	16598	-1.752	-0.4693	No
188	CTNNB1	16702	-1.841	-0.4731	No
189	SHC1	16723	-1.857	-0.4731	No
190	HDAC1	16830	-1.955	-0.4769	No
191	ATF6	16839	-1.964	-0.4763	No
192	RPS6KA4	16863	-1.997	-0.4763	No
193	PRKCH	16959	-2.083	-0.4796	No
194	TRAF6	16980	-2.105	-0.4795	No
195	NR3C1	17008	-2.137	-0.4796	No
196	AKT1	17066	-2.193	-0.4811	No
197	RHOA	17075	-2.199	-0.4803	No
198	E2F4	17086	-2.203	-0.4796	No
199	MITF	17114	-2.231	-0.4797	No
200	PRKG1	17162	-2.273	-0.4807	No
201	MAP3K7IP1	17192	-2.295	-0.4808	No
202	MAPK9	17214	-2.310	-0.4806	No
203	ERC1	17266	-2.356	-0.4817	No
204	TIAM1	17271	-2.359	-0.4807	No
205	PTPN6	17353	-2.437	-0.4832	No
206	CALM3	17354	-2.438	-0.4819	No
207	MAPKAPK3	17357	-2.443	-0.4807	No
208	MAP3K14	17377	-2.462	-0.4803	No
209	PRKAB1	17420	-2.502	-0.4810	No
210	FOXP3	17466	-2.555	-0.4817	No
211	ZBTB17	17482	-2.582	-0.4811	No
212	RALA	17496	-2.599	-0.4803	No
213	PLEKHA1	17535	-2.637	-0.4807	No
214	NUP214	17596	-2.687	-0.4821	No
215	SNIP1	17597	-2.687	-0.4807	No
216	MAP2K6	17632	-2.723	-0.4808	No
217	CHUK	17643	-2.730	-0.4799	No
218	ELK1	17690	-2.773	-0.4805	No
219	CTBP1	17721	-2.801	-0.4805	No
220	PLEKHA2	17744	-2.825	-0.4800	No
221	PAK1	17746	-2.826	-0.4786	No
222	MAPK14	17811	-2.903	-0.4800	No
223	ARF5	17829	-2.926	-0.4793	No
224	RAB5A	17834	-2.930	-0.4779	No
225	MAP3K8	17860	-2.954	-0.4776	No
226	ARHGEF6	17905	-3.006	-0.4780	No
227	MAPK3	17962	-3.067	-0.4790	No
228	FKBP1A	17973	-3.076	-0.4779	No
229	MAPK11	18040	-3.143	-0.4793	No
230	FKBP8	18055	-3.159	-0.4783	No
231	AKT3	18133	-3.248	-0.4802	No
232	ARF1	18135	-3.249	-0.4785	No
233	DCP1A	18249	-3.380	-0.4820	No
234	BCL3	18305	-3.430	-0.4827	No
235	CAMK2A	18342	-3.465	-0.4826	No
236	MKNK1	18365	-3.498	-0.4818	No
237	IKBKG	18397	-3.530	-0.4814	No
238	SIN3A	18427	-3.568	-0.4809	No
239	SYK	18493	-3.653	-0.4820	No
240	PAG1	18498	-3.656	-0.4802	No
241	PRKCD	18528	-3.688	-0.4797	No
242	CBFB	18612	-3.770	-0.4815	No
243	YWHAB	18690	-3.865	-0.4831	No
244	MAP3K10	18760	-3.957	-0.4842	Yes
245	HDAC2	18791	-3.993	-0.4835	Yes
246	ATM	18851	-4.077	-0.4841	Yes
247	PAK2	18865	-4.102	-0.4826	Yes
248	EEF2	18879	-4.125	-0.4810	Yes
249	NCOA2	18910	-4.163	-0.4803	Yes
250	DAPP1	18923	-4.178	-0.4786	Yes
251	COPA	18949	-4.208	-0.4776	Yes
252	CREB1	18962	-4.227	-0.4759	Yes
253	PRKCA	18987	-4.255	-0.4748	Yes
254	ARRB2	19063	-4.371	-0.4760	Yes
255	RAF1	19074	-4.383	-0.4742	Yes
256	CTLA4	19075	-4.385	-0.4719	Yes
257	PRNP	19157	-4.513	-0.4733	Yes
258	FOS	19178	-4.546	-0.4718	Yes
259	PTEN	19245	-4.642	-0.4725	Yes
260	SRF	19248	-4.646	-0.4701	Yes
261	ARFGAP1	19249	-4.646	-0.4677	Yes
262	HBP1	19318	-4.762	-0.4684	Yes
263	MAP3K12	19326	-4.778	-0.4662	Yes
264	UBE2I	19367	-4.845	-0.4655	Yes
265	NR4A1	19386	-4.872	-0.4638	Yes
266	GADD45A	19391	-4.881	-0.4615	Yes
267	SLC9A1	19431	-4.942	-0.4607	Yes
268	DDIT3	19452	-4.972	-0.4590	Yes
269	NFKB2	19492	-5.020	-0.4582	Yes
270	PTPRC	19517	-5.062	-0.4567	Yes
271	CSNK1A1	19558	-5.138	-0.4558	Yes
272	EIF4E	19561	-5.139	-0.4532	Yes
273	BIRC2	19566	-5.145	-0.4507	Yes
274	MDM2	19572	-5.152	-0.4483	Yes
275	DUSP1	19595	-5.181	-0.4466	Yes
276	CD79B	19598	-5.186	-0.4440	Yes
277	ARF6	19599	-5.188	-0.4413	Yes
278	CBLB	19603	-5.196	-0.4387	Yes
279	AXIN1	19618	-5.227	-0.4366	Yes
280	MAPKAP1	19631	-5.246	-0.4344	Yes
281	ATF2	19713	-5.352	-0.4354	Yes
282	IKBKB	19718	-5.359	-0.4328	Yes
283	RUNX2	19721	-5.364	-0.4300	Yes
284	CAMK4	19772	-5.438	-0.4295	Yes
285	CYLD	19870	-5.610	-0.4311	Yes
286	CTDSP2	19900	-5.658	-0.4295	Yes
287	YWHAZ	19925	-5.718	-0.4276	Yes
288	PTPN1	20053	-5.976	-0.4304	Yes
289	VAV1	20066	-6.018	-0.4278	Yes
290	GOSR2	20110	-6.089	-0.4266	Yes
291	RUNX1	20112	-6.091	-0.4235	Yes
292	GATA3	20113	-6.093	-0.4203	Yes
293	CTDSP1	20120	-6.107	-0.4174	Yes
294	AP2M1	20168	-6.215	-0.4163	Yes
295	YWHAH	20180	-6.225	-0.4135	Yes
296	PLCG1	20195	-6.259	-0.4109	Yes
297	AKT2	20209	-6.297	-0.4082	Yes
298	BCL10	20231	-6.352	-0.4059	Yes
299	MAP3K7IP2	20281	-6.446	-0.4048	Yes
300	PPP3CB	20348	-6.597	-0.4044	Yes
301	TBC1D4	20378	-6.661	-0.4023	Yes
302	RELB	20410	-6.758	-0.4002	Yes
303	ARHGEF7	20413	-6.769	-0.3967	Yes
304	MAP3K3	20422	-6.791	-0.3936	Yes
305	SKIL	20440	-6.832	-0.3908	Yes
306	VAV2	20452	-6.862	-0.3877	Yes
307	PKN1	20455	-6.883	-0.3842	Yes
308	PPP2CA	20473	-6.912	-0.3814	Yes
309	PIK3CA	20532	-7.036	-0.3804	Yes
310	FBXW11	20554	-7.084	-0.3777	Yes
311	MAPKAPK5	20596	-7.204	-0.3758	Yes
312	GBF1	20604	-7.224	-0.3723	Yes
313	PRKCE	20653	-7.365	-0.3707	Yes
314	RBBP4	20687	-7.464	-0.3683	Yes
315	PML	20746	-7.609	-0.3671	Yes
316	ELK4	20776	-7.731	-0.3644	Yes
317	EP300	20781	-7.751	-0.3605	Yes
318	SMAD4	20832	-7.924	-0.3587	Yes
319	RASA1	20833	-7.927	-0.3545	Yes
320	PPM1A	20886	-8.120	-0.3527	Yes
321	PRKCQ	20917	-8.226	-0.3498	Yes
322	DUSP16	20921	-8.252	-0.3456	Yes
323	NCOA1	20923	-8.265	-0.3413	Yes
324	CSNK2A1	20926	-8.269	-0.3371	Yes
325	SMURF2	20932	-8.289	-0.3330	Yes
326	ETS1	20973	-8.470	-0.3304	Yes
327	TRAF2	21018	-8.648	-0.3280	Yes
328	RELA	21022	-8.671	-0.3236	Yes
329	TGFBR2	21043	-8.737	-0.3199	Yes
330	TAOK3	21049	-8.758	-0.3156	Yes
331	NUP153	21076	-8.855	-0.3122	Yes
332	GGA3	21109	-8.959	-0.3090	Yes
333	ITCH	21112	-8.974	-0.3044	Yes
334	SMAD7	21156	-9.164	-0.3016	Yes
335	NRAS	21157	-9.167	-0.2968	Yes
336	NCOR1	21158	-9.168	-0.2920	Yes
337	LAMC1	21167	-9.223	-0.2875	Yes
338	RALB	21174	-9.233	-0.2830	Yes
339	CARD11	21186	-9.295	-0.2786	Yes
340	CD4	21188	-9.300	-0.2738	Yes
341	MAPK8	21208	-9.408	-0.2698	Yes
342	NEDD4L	21211	-9.420	-0.2650	Yes
343	CLTA	21272	-9.721	-0.2627	Yes
344	CDKN1B	21294	-9.870	-0.2585	Yes
345	JUNB	21298	-9.897	-0.2534	Yes
346	FYN	21301	-9.911	-0.2484	Yes
347	ITK	21334	-10.083	-0.2446	Yes
348	TSC1	21353	-10.209	-0.2401	Yes
349	EGR1	21359	-10.247	-0.2350	Yes
350	TGFBR1	21368	-10.287	-0.2299	Yes
351	BCL2	21371	-10.300	-0.2247	Yes
352	FRAP1	21383	-10.384	-0.2197	Yes
353	GADD45B	21406	-10.572	-0.2152	Yes
354	CREBBP	21411	-10.605	-0.2099	Yes
355	CSK	21416	-10.654	-0.2045	Yes
356	HSP90AA1	21420	-10.699	-0.1990	Yes
357	MEF2A	21429	-10.782	-0.1938	Yes
358	GSK3B	21455	-10.935	-0.1892	Yes
359	MAP2K4	21466	-10.991	-0.1839	Yes
360	RPS6KB1	21479	-11.098	-0.1787	Yes
361	RNF111	21480	-11.117	-0.1729	Yes
362	TNFAIP3	21482	-11.148	-0.1671	Yes
363	NFATC1	21534	-11.557	-0.1634	Yes
364	PIAS4	21535	-11.560	-0.1574	Yes
365	CCM2	21538	-11.589	-0.1514	Yes
366	SIN3B	21555	-11.732	-0.1460	Yes
367	GDI1	21614	-12.478	-0.1422	Yes
368	LSP1	21678	-13.330	-0.1382	Yes
369	TNFRSF1A	21703	-13.816	-0.1321	Yes
370	MEF2D	21742	-14.522	-0.1262	Yes
371	NFATC3	21743	-14.538	-0.1186	Yes
372	NFKBIA	21775	-15.114	-0.1122	Yes
373	LCK	21778	-15.166	-0.1043	Yes
374	MAP3K1	21803	-15.769	-0.0972	Yes
375	SP1	21811	-15.984	-0.0892	Yes
376	YWHAE	21814	-16.134	-0.0808	Yes
377	TAOK2	21830	-16.810	-0.0727	Yes
378	SKI	21861	-17.840	-0.0648	Yes
379	MALT1	21871	-18.066	-0.0558	Yes
380	PDPK1	21879	-18.696	-0.0463	Yes
381	TGFBR3	21891	-19.317	-0.0368	Yes
382	DGKA	21928	-24.490	-0.0256	Yes
383	EGR3	21930	-24.862	-0.0127	Yes
384	EGR2	21933	-25.685	0.0006	Yes